Rsk2 Triple Negative Breast Cancer

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Synaptotagmin-like 2 isoform a;Breast cancer-associated antigen SGA-72M;synaptotagmin-like 2 isoform c;synaptotagmin-like 2 isoform d; triple functional domain;Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein). ... Read Document

Presentation Title: Antioxidants Decrease The Apoptotic ...
Presentation Title: Antioxidants decrease the apoptotic effect of 5-Fu in colon cancer especially the triple negative breast cancer (TNBC),which most easily RSK2 and MSK1 at the ATP-binding pocket and inhibits their respective ... Read More

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32 28 0.15212999999999999 0.10324999999999999. 12 12 0.16286999999999999 0.51422000000000001. 6 6 0.19986999999999999 2.4735. 3 3 0.23591000000000001 0.35809000000000002. 32 22 0. ... View This Document

Inhibition Of RSK With The Novel Small-molecule Inhibitor ...
The triple-negative breast cancer (TNBC) subtype is enriched in cancer stem cells (CSCs) and clinically correlated with the highest rate of recurrence. (encoding RSK2) as being absolutely required to sustain the growth of estrogen-receptor ... Read Full Source

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Breast cancer-associated protein SGA-113M;p42A;Phosphonoformate immuno-associated protein 4;Proteasome regulatory particle subunit p44S10;KIAA0107 isoform;Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6, isoform CRA_d; ... Get Doc

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Proteomic analysis in human breast cancer: Overexpression of ER and VDR is not sufficient to make ER-negative MDA-MB231 breast cancer cells responsive to 1 HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK2, pp90RSK3 NCBI Entrez Gene ID = 6196 H00056949-M01 XAB2 monoclonal ... Doc Viewer

Subject: My Team Wants You! - Supportcbcf.com
(†) Canadian Breast Cancer Foundation, Subject: My Team Wants You! Come and join [team name] in the 2014 Canadian Breast Cancer Foundation CIBC Run for the Cure. (RSK2) that is essential to the growth of TNBC cells, and have given drug ... Access Doc

Www.wjgnet.com
In HNSCC patients, expression of RSK2 and FSCN1 proteins correlate closely. Williams C. miR-206 inhibits cell migration through direct targeting of the actin-binding protein coronin 1C in triple-negative breast cancer. ... View Document

Projects For The PhD Students Recruitment In Academic Year ...
Projects for the PhD students recruitment in academic year 2013/2014 Clinical and biological significance of RSK2 kinase in breast cancer progression. (Triple-Negative Breast Cancer). ... Fetch Doc

Game-Changing Discovery In Triple-Negative Breast Cancer ...
Game-Changing Discovery in Triple-Negative Breast Cancer Published in Stem Cells Journal EMBARGOED until Tuesday, June 5, 9:00am Pacific Standard Time "RSK2 inhibition provides a novel therapeutic avenue for TNBC and holds the promise of being one of the ... Read Here

2015 OPEN ACCESS Pharmaceuticals - MDPI
Pharmaceuticals 2015, 8, 455-473; doi:10.3390/ph8030455 pharmaceuticals [15]. PEA-15 binds to p90 ribosomal S6 kinase isozyme 2 (RSK2), but not RSK1 [16], and it inhibits tumorigenesis in triple-negative breast cancer [39], ... Fetch Here

AEZS-131 - A Highly Selective ERK-inhibitor: Characterization ...
Characterization and preclinical testing in triple negative breast cancer (TNBC) Engel JB1, Seipelt I*, Hönig A2, Hahne JC2, Teifel M* 1: Medical University of Regensburg, Dept. of OB/Gyn; 2: Medical University of Würzburg , Dept. of OB/Gyn; *: Aeterna/Zentari s, Frankfurt ... Document Retrieval

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Pierce Negative Ion Calibration Solution, 10mL 88325 Pierce Triple Quadrupole Calibration Solution, 10mL 88330 1-Step Heavy Protein IVT Kit, 8-rxn kit 88331 1-Step Heavy Protein IVT Kit, 40-rxn kit 88400 Slide-A-Lyzer MINI Dialysis Device, 3.5K MWCO, 0.5mL, 25 devices ... Retrieve Doc

Img52.chem17.com
Breast cancer plex beckman rna 32b amb rna custom bulk t32 a32725 metastasis plex beckman rna a32750 alexa fluor 488 reactive dye d 1 set a32755 alexa fluor 555 and al a32756 alexa fluor 555 reacti a32757 alexa fluor 647 reacti a32761 aha-dutp (5-aminohexylacrylami 50 ul ... Retrieve Full Source

Targeting P90 Ribosomal S6 Kinase Eliminates Tumor-Initiating ...
The treatment of triple-negative breast cancer (TNBC) suffers from the lack of targeted therapies. Unlike estrogen receptor Activated RSK is expressed in triple-negative breast cancer patient samples. (A): RSK2 mRNA was associated with poor survival in ... Document Retrieval

TUMOR METASTASIS - American Association For Cancer Research
TUMOR METASTASIS November 30-December 3, 2015 Poster Session B B15 RSK2 signals through stathmin to promote microtubule dynamics and tumor B43 ADAM12 is a novel regulator of stem-like cells in triple-negative breast cancer. Yue Qi, Sara Duhachek-Muggy, Hui Li, Linda ... View Full Source

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Sheet2 GENE length (nt) TSA entry submitted TSA annotation D. melanogaster blastx hit FBgn number General Function Detailed Function SFAM# SFAM Pfam Clan# ... Access Doc

Luteolin Is A Novel P90 Ribosomal S6 Kinase (RSK) Inhibitor ...
Keywords: Triple-negative breast cancer, p90 ribosomal S6 kinase, Y-box binding protein-1, genome-wide screen for breast cancer subtype-specific inhibitors, RSK2 was one of only three molecules found to be important for sustaining the growth of TNBC [11]. ... Doc Retrieval

Review Annals Of Oncology
Have shown promising activity in breast cancer patients with FGFR1 and/or FGF3 amplification. Early clinical trials with se- roles in cancer cell proliferation, migration, angiogenesis, and survival. The FGFR pathway was primarily studied in cancer as ... Return Doc

PEA15 (phosphoprotein Enriched In Astrocytes 15)
Section of Translational Breast Cancer Research, Department of Breast Medical Oncology, amino acid position 74, 121, 123, and 129; RSK2 binding site: amino acid position 123; Serine 104: phosphorylation site by PKC; Serine 116: phosphorylation grade and with negative hormone receptor ... Fetch Document